Cortisone, Hydrocortisone, Prednisone, Prednisolone and Related Corticosteroids

Each compound — cortisone (2937210010), hydrocortisone (2937210020), prednisone (2937210030), and prednisolone (2937210040) — is a distinct chemical entity with its own CAS number, pharmacological profile, and commercial market. The granular breakdown allows CBP and FDA to track trade flows by specific substance, which is important for both statistical purposes and enforcement of any trade-remedy or admissibility measures that may apply to individual compounds.

FDA expects a certificate of analysis confirming identity, purity, and compliance with USP or equivalent pharmacopeial standards; the manufacturer's FDA facility registration number; and, where applicable, a Drug Master File (DMF) reference number. Shipments from facilities not registered with FDA or subject to import alert are subject to refusal of admission. Consulting a licensed customs broker with pharmaceutical import experience is advisable before the first shipment.