Harmonized System
U.S. imports of Vaccines, Toxins, Microbial Cultures & Related Biological Products (NESOI) (HS 300249) totaled $161.8M in August 2026, imported from 32 countries.
Importers of Vaccines, Toxins, Microbial Cultures & Related Biological Products (NESOI) paid $380K in duties in August 2026, an average duty rate of 0.23% — duty actually collected as a share of the imports that cleared customs, not the published tariff schedule. Vaccines, Toxins, Microbial Cultures & Related Biological Products (NESOI) imports of $161.8M in August 2026 ran 81% above the year-to-date monthly average of $89.3M.
Last updated: August 2026 dataResidual biological preparations — including microbial cultures, toxins not elsewhere specified, and other vaccines outside the dedicated human and veterinary headings — are captured here, along with the specifically enumerated tariff line for ricin (3002490010), a select agent subject to strict CDC and USDA oversight. Ireland, Belgium, and Germany are the primary US source countries for the broader NESOI category (3002490050), consistent with Europe's dominant role in advanced biologics manufacturing. Importers of microbial cultures and toxins must navigate both FDA biologics regulations and, where applicable, CDC/USDA select-agent program requirements, which impose registration, security, and transfer restrictions well beyond standard pharmaceutical entry procedures.
AI-written summary of the official U.S. Census Bureau trade figures on this page — verify before relying on it.
909 import shipments a month
Ricin is classified as a CDC/USDA select agent, meaning its possession, use, and transfer are regulated under the Federal Select Agent Program. Importers must be registered with the appropriate federal select-agent program, obtain prior approval for transfer, and maintain strict security and inventory controls. Standard FDA pharmaceutical import procedures are insufficient — select-agent compliance is a separate, parallel requirement.
Classification depends on the culture's intended use and presentation. Cultures intended for therapeutic or prophylactic use in humans typically fall within Chapter 30, while cultures for industrial fermentation or research may classify elsewhere (e.g., Chapter 21 or 38). A licensed customs broker with pharmaceutical experience should review the product's technical documentation, including its intended use and regulatory status, before filing entry.
Subheading 5 of 10 in heading 3002
Subheading 300249 · $161.8M of $5.8B
Trade Directory
List your company under HS 300249 — Vaccines, Toxins, Microbial Cultures & Related Biological Products (NESOI), so the companies trading it can find you. Be the first supplier listed.
HS10 import codes under this HS6 parent, each with its own page. Source: U.S. Harmonized Tariff Schedule.
| Code | Description | Imports for consumption | Average duty rate | Dutiable Share | Duty Collected |
|---|---|---|---|---|---|
| 3002490050 | Vaccines, Toxins, Cultures of Micro-Organism Etc Nes | $161.7M | 0.23% | 1.16% | $380K |
| 3002490010 | Ricin | $58K | 0.00% | 0.00% | -- |
HS10 export codes under this HS6 parent, each with its own page. Source: U.S. Schedule B export classification.
| Code | Description | Export Value |
|---|---|---|
| 3002490050 | Vaccines, Toxins, Cultures of Micro-Organism Etc Nes | $187.4M |
| 3002490010 | Ricin | $1.6M |
Import lines come from the U.S. Harmonized Tariff Schedule and export lines from Schedule B. The two are numbered by different agencies, so the same 10-digit code can appear in both tables describing a different product.
ImportsExports
Imports
$161.8MYoY · free account
Exports
$189.0MYoY · free account
12-mo low · imports
Low · free accountOver the twelve months to August 2026, the U.S. imported $1.3B of Vaccines, Toxins, Microbial Cultures & Related Biological Products (NESOI) and exported $1.7B.
Through August 2026. Source: U.S. Census Bureau.
Imports · August 2026
origin
United Kingdom and South Korea together supply 64% of it.
customs district
destination
entry
rate provision · imports
98.8% enters free of duty; duty collected equals 0.23% of imports for consumption.