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HSChapter 29
U.S. imports of theophylline, aminophylline & their derivatives and salts (HS 293959) totaled $259K in April 2026, traded with 5 countries.
Last updated: April 2026 dataTheophylline and aminophylline are xanthine-class bronchodilator APIs used in respiratory therapeutics, and their derivatives and salts enter under a single tariff line (2939590000). India and China are the leading suppliers, with Italy, Germany, and the Netherlands also contributing to US import flows. FDA entry review applies because these substances are active pharmaceutical ingredients subject to cGMP requirements; importers must ensure the foreign manufacturer holds an FDA Drug Establishment Registration and that each lot is accompanied by appropriate certificates of analysis. Supply-chain concentration among a handful of Asian API producers makes quality-system audits a critical risk-management tool.
AI-written summary of the official U.S. Census Bureau trade figures on this page — verify before relying on it.
Foreign establishments that manufacture, process, pack, or hold drug substances for US import must register with FDA under the Drug Establishment Registration program and list their drug products. Shipments from unregistered facilities are subject to refusal of admission.
Aminophylline is a theophylline-ethylenediamine complex, while other derivatives may be distinct salts or chemical modifications. All fall under 2939590000 as long as they are derivatives or salts of theophylline or aminophylline not more specifically provided for elsewhere; importers with novel derivatives should seek a binding ruling to confirm classification.
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Monthly import values over time
HS10 import codes under this HS6 parent. Source: U.S. Harmonized Tariff Schedule.
| Code | Description | Import Value | Effective Tariff % |
|---|---|---|---|
| 2939590000 | THEOPHYLLINE & AMINOPHYLLINE & DERIVS, SALTS NESOI | $259K | -- |
THEOPHYLLINE & AMINOPHYLLINE & DERIVS, SALTS NESOI
HS10 export codes under this HS6 parent. Source: U.S. Schedule B export classification.
| Code | Description | Export Value |
|---|---|---|
| 2939590000 | THEOPHYLLINE & AMINOPHYLLINE & DERIVS, SALTS NESOI | $12K |
THEOPHYLLINE & AMINOPHYLLINE & DERIVS, SALTS NESOI
27 kg
NUCLEIC ACIDS & SALTS; OTHER HETEROCYCLIC CMP, NES
HS 293499
HETEROCYCLIC COMP W NITROGEN HETERO-ATM ONLY NESOI
HS 293399
POLYPEPTIDE PROTEIN& GLYCOPROTEIN HORMONES &DERIV
HS 293719
CMPDS CONT AN UNFUSED PYRIDINE RING ETC NESOI
HS 293339
COMP WITH PYRIMIDINE OR PIPERAZINE RING, NESOI
HS 293359
ANTIBIOTICS, NESOI
HS 294190
| State | Imports | Exports | Balance |
|---|---|---|---|
| California | $118K | -- | -$118K |
| Pennsylvania | $90K | -- | -$90K |
| New Jersey | $30K | -- | -$30K |
| Port | Imports | Exports | Balance |
|---|---|---|---|
| LOS ANGELES, CA | $118K | -- | -$118K |
| JFK INTERNATIONAL AIRPORT, NY | $105K | -- | -$105K |
| NEWARK, NJ | $30K | -- | -$30K |