U.S. imports of Medicaments Containing Other Alkaloids or Derivatives, in Measured Doses for Retail Sale (NESOI) (HS 300449) totaled $69.7M in August 2026, imported from 32 countries.
Importers of Medicaments Containing Other Alkaloids or Derivatives, in Measured Doses for Retail Sale (NESOI) paid $232K in duties in August 2026, an average duty rate of 0.34% — duty actually collected as a share of the imports that cleared customs, not the published tariff schedule. Medicaments Containing Other Alkaloids or Derivatives, in Measured Doses for Retail Sale (NESOI) imports of $69.7M in August 2026 ran 16% above the year-to-date monthly average of $59.9M.
Last updated: August 2026 dataAlkaloid-based medicaments not captured by the ephedrine, pseudoephedrine, or norephedrine headings are classified here, spanning a therapeutically diverse range of finished-dose products. The US schedule subdivides this heading into eight 10-digit tariff lines by therapeutic category: veterinary use (3004490005), cardiovascular agents (3004490010), anticonvulsants/hypnotics/sedatives (3004490020), antidepressants/tranquilizers/psychotropic agents (3004490030), other CNS-affecting medicaments (3004490040), dermatological agents and local anesthetics (3004490050), ophthalmic/otic/respiratory agents (3004490060), and a residual catch-all (3004490070). Correct classification requires identifying both the alkaloid active ingredient and the primary therapeutic indication, as the same alkaloid may fall into different lines depending on its labeled use. Many lines in this heading contain controlled substances or psychotropic compounds subject to DEA scheduling.
AI-written summary of the official U.S. Census Bureau trade figures on this page — verify before relying on it.
665 import shipments a month
Dermatological agents and local anesthetics are specifically carved out under 3004490050. If the product's primary labeled indication is local anesthesia or a dermatological application and the active ingredient is an alkaloid or derivative, that line takes precedence over the residual 3004490070 catch-all.
Not universally, but many alkaloids and their derivatives — including opioids, benzodiazepines, and certain stimulants — are DEA-scheduled controlled substances. Importers must verify the DEA schedule of each active ingredient and obtain the appropriate import permit or quota authorization. Products not containing a scheduled substance still require FDA drug establishment registration for the foreign manufacturer. Admissibility is complex; consult a licensed customs broker and DEA/FDA regulatory counsel.
ImportsExports
Imports
$69.7MYoY · free account
Exports
$23.1MYoY · free account
12-mo low · imports
Low · free accountOver the twelve months to August 2026, the U.S. imported $795.0M of Medicaments Containing Other Alkaloids or Derivatives, in Measured Doses for Retail Sale (NESOI) and exported $219.1M.
Through August 2026. Source: U.S. Census Bureau.
Trade Directory
List your company under HS 300449 — Medicaments Containing Other Alkaloids or Derivatives, in Measured Doses for Retail Sale (NESOI), so the companies trading it can find you. Be the first supplier listed.
Subheading 5 of 12 in heading 3004
Subheading 300449 · $69.7M of $7.1B
HS10 import codes under this HS6 parent, each with its own page. Source: U.S. Harmonized Tariff Schedule.
| Code | Description | Imports for consumption | Average duty rate | Dutiable Share | Duty Collected |
|---|---|---|---|---|---|
| 3004490060 | Medicaments Affecting Eyes, Ears or Respiratory Sys | $27.7M | 0.70% | 6.51% | $194K |
| 3004490040 | Other Medicaments Prim Affecting the Cns NESOI | $13.6M | 0.01% | 0.12% | $2K |
| 3004490010 | Cardiovasc Medicaments(Mix/Unmix)Cont Alkal/Drvatv | $13.2M | 0.03% | 0.23% | $4K |
| 3004490030 | Antidepressants, Tranquilizers, Psych Agt, No Hormone | $6.1M | 0.00% | 0.00% | -- |
| 3004490020 | Anticonvulsants, Hypnotics, Sedatives, Doses for Sale | $2.7M | 0.00% | 0.00% | -- |
| 3004490070 | Other Medicaments Containing Alkaloids Etc | $2.1M | 1.49% | 11.91% | $32K |
| 3004490050 | Dermatological Agents and Local Anesthetics | $1.8M | 0.00% | 0.00% | -- |
| 3004490005 | Medicaments(Mix/Unmix)Cont Alkloid/Derivt-Vet Use | $1.1M | 0.00% | 0.00% | -- |
HS10 export codes under this HS6 parent, each with its own page. Source: U.S. Schedule B export classification.
Import lines come from the U.S. Harmonized Tariff Schedule and export lines from Schedule B. The two are numbered by different agencies, so the same 10-digit code can appear in both tables describing a different product.
Imports · August 2026
origin
India and Germany together supply 62% of it.
customs district
destination
entry
rate provision · imports
71.7% enters free of duty; duty collected equals 0.34% of imports for consumption.