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HSChapter 30
U.S. imports of medicaments containing other alkaloids or derivatives, in measured doses for retail sale (nesoi) (HS 300449) totaled $44.9M in April 2026, traded with 30 countries.
Importers of Medicaments Containing Other Alkaloids or Derivatives, in Measured Doses for Retail Sale (NESOI) paid $173K in duties in April 2026 — an effective duty rate of 10% on $1.7M in dutiable value, based on actual customs collections rather than the published tariff schedule. Medicaments Containing Other Alkaloids or Derivatives, in Measured Doses for Retail Sale (NESOI) imports of $44.9M in April 2026 ran 26% below the year-to-date monthly average of $60.5M.
Last updated: April 2026 dataAlkaloid-based medicaments not captured by the ephedrine, pseudoephedrine, or norephedrine headings are classified here, spanning a therapeutically diverse range of finished-dose products. The US schedule subdivides this heading into eight 10-digit tariff lines by therapeutic category: veterinary use (3004490005), cardiovascular agents (3004490010), anticonvulsants/hypnotics/sedatives (3004490020), antidepressants/tranquilizers/psychotropic agents (3004490030), other CNS-affecting medicaments (3004490040), dermatological agents and local anesthetics (3004490050), ophthalmic/otic/respiratory agents (3004490060), and a residual catch-all (3004490070). Correct classification requires identifying both the alkaloid active ingredient and the primary therapeutic indication, as the same alkaloid may fall into different lines depending on its labeled use. Many lines in this heading contain controlled substances or psychotropic compounds subject to DEA scheduling.
AI-written summary of the official U.S. Census Bureau trade figures on this page — verify before relying on it.
Dermatological agents and local anesthetics are specifically carved out under 3004490050. If the product's primary labeled indication is local anesthesia or a dermatological application and the active ingredient is an alkaloid or derivative, that line takes precedence over the residual 3004490070 catch-all.
Not universally, but many alkaloids and their derivatives — including opioids, benzodiazepines, and certain stimulants — are DEA-scheduled controlled substances. Importers must verify the DEA schedule of each active ingredient and obtain the appropriate import permit or quota authorization. Products not containing a scheduled substance still require FDA drug establishment registration for the foreign manufacturer. Admissibility is complex; consult a licensed customs broker and DEA/FDA regulatory counsel.
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Monthly import values over time
HS10 import codes under this HS6 parent. Source: U.S. Harmonized Tariff Schedule.
| Code | Description | Import Value | Effective Tariff % | Duty Collected |
|---|---|---|---|---|
| 3004490060 | MEDICAMENTS AFFECTING EYES,EARS OR RESPIRATORY SYS | $20.0M | 10.00% | $117K |
| 3004490010 | CARDIOVASC MEDICAMENTS(MIX/UNMIX)CONT ALKAL/DRVATV | $8.5M | -- | -- |
| 3004490040 | OTHER MEDICAMENTS PRIM AFFECTING THE CNS NESOI | $6.3M | -- | -- |
| 3004490070 | OTHER MEDICAMENTS CONTAINING ALKALOIDS ETC | $4.1M | 10.00% | $56K |
| 3004490020 | ANTICONVULSANTS,HYPNOTICS,SEDATIVES,DOSES FOR SALE | $2.4M | -- | -- |
| 3004490030 | ANTIDEPRESSANTS,TRANQUILIZERS,PSYCH AGT,NO HORMONE | $2.3M | -- | -- |
| 3004490050 | DERMATOLOGICAL AGENTS AND LOCAL ANESTHETICS | $948K | -- | -- |
| 3004490005 | MEDICAMENTS(MIX/UNMIX)CONT ALKLOID/DERIVT-VET USE | $336K | -- | -- |
MEDICAMENTS AFFECTING EYES,EARS OR RESPIRATORY SYS
CARDIOVASC MEDICAMENTS(MIX/UNMIX)CONT ALKAL/DRVATV
OTHER MEDICAMENTS PRIM AFFECTING THE CNS NESOI
OTHER MEDICAMENTS CONTAINING ALKALOIDS ETC
ANTICONVULSANTS,HYPNOTICS,SEDATIVES,DOSES FOR SALE
ANTIDEPRESSANTS,TRANQUILIZERS,PSYCH AGT,NO HORMONE
DERMATOLOGICAL AGENTS AND LOCAL ANESTHETICS
MEDICAMENTS(MIX/UNMIX)CONT ALKLOID/DERIVT-VET USE
HS10 export codes under this HS6 parent. Source: U.S. Schedule B export classification.
| Code | Description | Export Value |
|---|---|---|
| 3004490040 | OTHER MEDICAMENTS PRIM AFFECTING THE CNS NESOI | $5.0M |
| 3004490060 | MEDICAMENTS AFFECTING EYES,EARS OR RESPIRATORY SYS | $2.7M |
| 3004490030 | ANTIDEPRESSANTS,TRANQUILIZERS,PSYCH AGT,NO HORMONE | $1.2M |
| 3004490070 | OTHER MEDICAMENTS CONTAINING ALKALOIDS ETC | $1.0M |
| 3004490010 | CARDIOVASC MEDICAMENTS(MIX/UNMIX)CONT ALKAL/DRVATV | $912K |
| 3004490020 | ANTICONVULSANTS,HYPNOTICS,SEDATIVES,DOSES FOR SALE | $762K |
| 3004490050 | DERMATOLOGICAL AGENTS AND LOCAL ANESTHETICS | $738K |
| 3004490005 | MEDICAMENTS(MIX/UNMIX)CONT ALKLOID/DERIVT-VET USE | $0 |
OTHER MEDICAMENTS PRIM AFFECTING THE CNS NESOI
17.9K kg
MEDICAMENTS AFFECTING EYES,EARS OR RESPIRATORY SYS
4.6K kg
ANTIDEPRESSANTS,TRANQUILIZERS,PSYCH AGT,NO HORMONE
8.3K kg
OTHER MEDICAMENTS CONTAINING ALKALOIDS ETC
24.6K kg
CARDIOVASC MEDICAMENTS(MIX/UNMIX)CONT ALKAL/DRVATV
1.9K kg
ANTICONVULSANTS,HYPNOTICS,SEDATIVES,DOSES FOR SALE
780 kg
DERMATOLOGICAL AGENTS AND LOCAL ANESTHETICS
11.9K kg
MEDICAMENTS(MIX/UNMIX)CONT ALKLOID/DERIVT-VET USE
IMMUNOLOGICAL PRODUCTS, MIXED, NOT IN MSRED DOSES
HS 300214
| Port | Imports | Exports | Balance |
|---|---|---|---|
| NEWARK, NJ | $9.9M | $368K | -$9.5M |
| NORFOLK-NEWPORT NEWS, VA | $9.0M | -- | -$9.0M |
| JFK INTERNATIONAL AIRPORT, NY | $4.7M | $2.5M | -$2.2M |