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HSChapter 29
U.S. imports of mannitol (HS 290543) totaled $4.2M in June 2026, traded with 7 countries.
Importers of Mannitol paid $657K in duties in June 2026 — an effective duty rate of 15% on $4.2M in dutiable value, based on actual customs collections rather than the published tariff schedule. Mannitol imports of $4.2M in June 2026 ran 42% above the year-to-date monthly average of $3.0M.
Mannitol (also called mannite) is a sugar alcohol used extensively as a pharmaceutical excipient — particularly as a diluent in tablet formulations and as an osmotic diuretic in injectable preparations — as well as a low-calorie sweetener in food applications. USDA FSIS does not govern this product, but FDA oversight applies to pharmaceutical-grade and food-grade imports, and foreign manufacturers supplying those markets must be registered with FDA. France and China are the leading US suppliers, with Italy and Germany also significant sources. Importers should ensure that pharmaceutical-grade mannitol is sourced from FDA-registered facilities and accompanied by a full certificate of analysis meeting USP or EP specifications.
AI-written summary of the official U.S. Census Bureau trade figures on this page — verify before relying on it.
Foreign manufacturers of pharmaceutical-grade mannitol must be registered with FDA under the Drug Listing and Establishment Registration requirements. Shipments intended for pharmaceutical use are subject to FDA examination at the port of entry, and the importer should be prepared to provide a certificate of analysis, batch records, and evidence of GMP compliance. FDA may detain shipments from unregistered facilities or those with prior compliance violations. Consulting a licensed customs broker experienced in pharmaceutical chemical imports is advisable.
Mannitol and sorbitol are stereoisomers — both are C6 sugar alcohols but differ in the spatial arrangement of one hydroxyl group. They are classified under separate HS6 headings (290543 for mannitol, 290544 for sorbitol) and separate 10-digit HTS lines. The distinction must be confirmed by the supplier's certificate of analysis, as the two compounds can appear similar in physical form but have different pharmaceutical and food applications.
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Monthly import values over time
HS10 import codes under this HS6 parent, each with its own page. Source: U.S. Harmonized Tariff Schedule.
| Code | Description | Import Value | Effective Tariff % | Dutiable Share | Duty Collected |
|---|---|---|---|---|---|
| 2905430000 | MANNITOL | $4.2M | 15.48% | 99.94% | $657K |
HS10 export codes under this HS6 parent, each with its own page. Source: U.S. Schedule B export classification.
| Code | Description | Export Value |
|---|---|---|
| 2905430000 | MANNITOL (MANNITE) | $2.1M |
NUCLEIC ACIDS & SALTS; OTHER HETEROCYCLIC CMP, NES
HS 293499
POLYPEPTIDE PROTEIN& GLYCOPROTEIN HORMONES &DERIV
HS 293719
CMPDS CONT AN UNFUSED PYRIDINE RING ETC NESOI
HS 293339
BENZENE
HS 290220
HETEROCYCLIC COMP W NITROGEN HETERO-ATM ONLY NESOI
HS 293399
HETEROCYCLIC COMP WITH UNFUSED PYRAZOLE RING NESOI
HS 293319
| State | Imports | Exports | Balance |
|---|---|---|---|
| Michigan | $1.8M | $319K | -$1.4M |
| New Jersey | $1.2M | -- | -$1.2M |
| Delaware | $170K | $577K | +$407K |
| Port | Imports | Exports | Balance |
|---|---|---|---|
| CHICAGO, IL | $1.9M | $55K | -$1.8M |
| LAREDO, TX | -- | $978K | +$978K |
| NEW YORK, NY | $931K | $7K | -$924K |