Yes. USDA APHIS classifies guinea fowls as poultry, so importers must obtain an import permit and present a health certificate from the exporting country's veterinary authority covering notifiable avian diseases. The same disease-status country requirements that apply to chickens and turkeys apply to guinea fowls.

Classification hinges on species identification and weight: guinea fowls at or below 185 grams fall under 0105150000, while heavier guinea fowls are captured in the residual over-185-gram subheading (0105990000). Accurate species documentation on the health certificate is important because guinea fowls can be confused with other helmeted game birds at visual inspection.