FDA's Center for Veterinary Medicine (CVM) has primary oversight of pet food safety and labeling. Foreign manufacturers must be registered with FDA under FSMA, and importers must maintain a Foreign Supplier Verification Program. Labels must comply with FDA pet food labeling regulations, including ingredient declarations and guaranteed analysis panels. If the product contains meat or poultry from certain countries, USDA APHIS may impose additional admissibility conditions.

Cambodia has become a significant contract manufacturing hub for wet pet food, particularly seafood-based varieties destined for the US market. Importers sourcing from Cambodia should conduct thorough supplier audits given the country's developing regulatory infrastructure, and should verify that facilities meet FDA registration and HACCP requirements. Concentration of supply in Southeast Asian origins — Thailand, Cambodia, and Vietnam collectively — also creates exposure to regional disruptions from weather events or regulatory changes.