Beryllium is a known carcinogen subject to OSHA's beryllium standard, which imposes strict exposure limits and handling requirements. Importers of beryllium-bearing ash or residues should ensure that safety data sheets accompany the shipment, that downstream handlers are informed of beryllium content, and that the material is transported in compliance with DOT hazardous materials regulations. EPA may also require notification for certain beryllium waste imports.

The HS nomenclature groups these metals together as a residual category for ash and residues not covered by the more specific subheadings for zinc, lead, copper, and aluminum. Despite their chemical differences, they share the characteristic of being minor-metal byproducts from specialty industrial processes, and their trade volumes are generally too small to warrant individual subheadings at the HS6 level.