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SITCSection 5
U.S. imports of theophylline, aminophylline, their derivatives, and salts (SITC 54145) totaled $70K in July 2026, traded with 5 countries.
Theophylline, Aminophylline, Their Derivatives, and Salts imports of $70K in July 2026 ran 73% below the year-to-date monthly average of $259K.
Last updated: July 2026 dataTheophylline — a methylxanthine bronchodilator chemically related to caffeine — and its ethylenediamine complex aminophylline are established APIs used in the treatment of asthma and chronic obstructive pulmonary disease. Both compounds have narrow therapeutic indices, making pharmaceutical-grade purity and consistent specification critical for downstream drug manufacturers. FDA cGMP requirements apply to imported bulk drug substances, and importers should verify that foreign suppliers hold current FDA facility registration and have not been placed on import alert.
AI-written summary of the official U.S. Census Bureau trade figures on this page — verify before relying on it.
2 shipments/mo
Basic heading 446 of 465 in section 5
Basic heading 54145 · $70K of $28.9B
Because theophylline's toxic dose is close to its therapeutic dose, even minor impurities or potency deviations in the bulk API can create patient safety risks in finished drug products. FDA inspectors pay close attention to analytical method validation and impurity profiles when reviewing cGMP compliance at foreign theophylline manufacturing sites.
At the SITC level they share a single heading, but the HTS schedule may distinguish them at the 10-digit level. Importers should confirm the correct HTS subheading with a licensed customs broker, as the specific compound and its salt form can affect duty treatment and statistical reporting.
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Imports · July 2026
origin
Italy and India together supply 100% of it.
customs district
Census does not publish district detail for this classification system.
destination
Census does not publish state detail for this classification system.
entry
Census does not publish port detail for this classification system.
ImportsExports
Imports
$70KYoY · Pro
Exports
$20KYoY · Pro
12-mo low · imports
YoY · ProFewer than 6 of the last 12 months reported trade above $500K; the trend chart is not shown for thin series.
Through July 2026. Source: U.S. Census Bureau.