Yes. Streptomycin registered for use on crops (e.g., to control fire blight in orchards) is regulated as a pesticide by the EPA under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). Importing streptomycin for agricultural use requires that the product be registered with EPA or qualify for an exemption, which is a separate compliance pathway from FDA's pharmaceutical drug import program. Importers should clearly identify the intended end use to determine which regulatory framework applies.

Streptomycin is produced by microbial fermentation rather than chemical synthesis, so batch-to-batch potency and impurity profiles depend heavily on fermentation conditions, strain quality, and downstream purification. Certificates of analysis should specify potency (in IU/mg or µg/mg), identified impurities, and residual solvent levels. These parameters also inform whether the material meets USP or BP pharmacopeial standards required for pharmaceutical-grade import.