SITCSection 5
U.S. imports of rye ergot alkaloids, derivatives, and their salts (SITC 54146) totaled $305K in April 2026, traded with 7 countries.
Rye Ergot Alkaloids, Derivatives, and Their Salts imports of $305K in April 2026 ran 16% below the year-to-date monthly average of $363K.
Last updated: April 2026 dataErgot alkaloids — produced by the fungus Claviceps purpurea on rye and other grains — include ergotamine, ergometrine, and lysergic acid, the last of which is a DEA Schedule III controlled substance and a precursor to LSD. Pharmaceutical derivatives such as ergotamine tartrate are used in migraine treatment and obstetric applications. DEA controls apply to lysergic acid and certain derivatives, requiring import permits, while other ergot alkaloids traded as pharmaceutical APIs are subject to FDA cGMP oversight. The dual regulatory exposure makes pre-import classification of the specific compound essential.
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Lysergic acid and its salts are DEA Schedule III controlled substances requiring import permits. Ergotamine, ergometrine, and most other pharmaceutical ergot derivatives are not DEA-scheduled but are regulated by FDA as drug APIs subject to cGMP and facility registration requirements. Importers must identify the specific compound before determining which agency's authorization is needed.
A shipment of ergotamine tartrate should be accompanied by a certificate of analysis confirming identity, purity, and compliance with pharmacopeial specifications, along with evidence that the foreign manufacturer is FDA-registered and cGMP-compliant. Customs entry documents should accurately describe the specific alkaloid and salt form to avoid misclassification delays.
| Country | Imports | Exports | Balance |
|---|---|---|---|
| CZECH REPUBLIC | $219K | -- | -$219K |
| ITALY | $78K | -- | -$78K |
| INDIA | -- | $7K | +$7K |
| HONG KONG | -- | $5K | +$5K |
| CANADA | $4K | -- | -$4K |
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Monthly import values over time