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SITCSection 5
U.S. imports of opium alkaloids, derivatives, and their salts (SITC 54141) totaled $15.4M in April 2026, traded with 15 countries.
Opium Alkaloids, Derivatives, and Their Salts imports of $15.4M in April 2026 ran 62% above the year-to-date monthly average of $9.5M.
Last updated: April 2026 dataOpium alkaloids — including morphine, codeine, thebaine, and their semi-synthetic derivatives — are tightly controlled at the federal level by the Drug Enforcement Administration (DEA) under the Controlled Substances Act, requiring import permits and quota authorization before any shipment can enter US commerce. FDA also reviews these substances as drug precursors or APIs. The combination of DEA scheduling, aggregate production quotas, and FDA cGMP requirements makes this one of the most compliance-intensive categories in pharmaceutical trade.
AI-written summary of the official U.S. Census Bureau trade figures on this page — verify before relying on it.
Importers must hold a DEA Schedule I or II importer registration, obtain a specific import permit for each shipment, and operate within DEA-established aggregate production quotas. The permit application must identify the foreign exporter, quantity, and intended US registrant recipient.
Thebaine is a controlled Schedule II precursor; it may be imported by a DEA-registered manufacturer for conversion into semi-synthetic opioids such as oxycodone or buprenorphine, but each import transaction requires its own DEA permit and must stay within the annual quota allocation for that substance.
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| Country | Imports | Exports | Balance |
|---|---|---|---|
| AUSTRALIA | $8.1M | $393K | -$7.7M |
| UNITED KINGDOM | $3.8M | $380K | -$3.4M |
| DENMARK | $1.4M | -- | -$1.4M |
| SPAIN | -- | $1.3M | +$1.3M |
| GERMANY | $1.3M | $7K | -$1.3M |
Monthly import values over time