Bulk antibiotic medicaments containing penicillins, streptomycins, or their derivatives — shipped in non-dosage, non-retail form — are classified here for use as pharmaceutical intermediates or active pharmaceutical ingredients (APIs) destined for further manufacturing. FDA oversight applies at entry, as these are drug substances subject to import alert and admissibility review under the Federal Food, Drug, and Cosmetic Act. Because these products are not yet in measured doses or retail packaging, they typically move through pharmaceutical supply chains as inputs to finished-drug production rather than as end-use products. Classification hinges on the specific antibiotic class present; penicillin or streptomycin derivatives must be confirmed to distinguish this heading from the broader antibiotic NES category.

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