Blood preparations are explicitly included in this heading regardless of the source animal, which is unusual — most adjacent headings are organized by species or cut type. This means dried blood powder, blood plasma concentrates, and cooked blood products from cattle, swine, poultry, or other animals can all fall here if not captured by a more specific provision. Importers should verify whether a blood-derived product has a dedicated HTS line before defaulting to the NES classification.

Classification rules generally require using the most specific applicable heading before resorting to a residual NES category. Importers should first determine whether the product's primary species (bovine, swine, poultry) and preparation method place it under a dedicated heading. Only when no specific heading applies should the NES category be used. Consulting a licensed customs broker and reviewing CBP binding ruling precedents for similar products is advisable to reduce misclassification risk.