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SITCSection 5
U.S. imports of cinchona alkaloids, derivatives, and their salts (SITC 54142) totaled $490K in April 2026, traded with 5 countries.
Cinchona Alkaloids, Derivatives, and Their Salts imports of $490K in April 2026 ran 61% above the year-to-date monthly average of $304K.
Last updated: April 2026 dataDerived from the bark of Cinchona trees native to South America, these alkaloids — principally quinine, quinidine, cinchonine, and cinchonidine — serve as APIs for antimalarial drugs and cardiac antiarrhythmics, as well as flavoring agents in tonic water at regulated concentrations. FDA governs pharmaceutical-grade imports as drug substances, while food-grade quinine used as a flavoring falls under separate food additive regulations with strict concentration limits. Importers should confirm whether a given shipment is destined for pharmaceutical or food use, as the applicable regulatory pathway and labeling requirements differ substantially.
AI-written summary of the official U.S. Census Bureau trade figures on this page — verify before relying on it.
No — food-grade quinine used as a flavoring in beverages is regulated under FDA food additive rules with a strict maximum use level, while pharmaceutical-grade quinine API is subject to drug cGMP requirements and facility registration. Misclassifying the intended use can trigger the wrong regulatory review at entry.
SITC 54142 is a statistical aggregation used in trade data; the actual US import declaration uses HTS Schedule B codes that distinguish between specific alkaloids (e.g., quinine vs. quinidine) and their salt forms. Importers should work with a licensed customs broker to identify the correct 10-digit HTS line, as duty rates and any applicable trade-remedy exposure can differ by specific compound.
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| Country | Imports | Exports | Balance |
|---|---|---|---|
| INDONESIA | $293K | $7K | -$286K |
| CHINA | $198K | -- | -$198K |
| CANADA | -- | $5K | +$5K |
| MADAGASCAR | -- | -- | -- |
| KOREA, SOUTH | -- | -- | -- |
Monthly import values over time