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HSChapter 29
U.S. imports of o-acetylsalicylic acid (aspirin), salts and esters (HS 291822) totaled $1.2M in June 2026, traded with 6 countries.
Importers of O-Acetylsalicylic Acid (Aspirin), Salts and Esters paid $77K in duties in June 2026 — an effective duty rate of 6.5% on $1.2M in dutiable value, based on actual customs collections rather than the published tariff schedule.
Aspirin — one of the world's most recognized active pharmaceutical ingredients — enters the US under this heading, which the US schedule subdivides into the pure acid (2918221000) and its salts and esters (2918225000). Because aspirin is a drug substance, shipments are subject to FDA admissibility review, and foreign manufacturers must be registered with FDA and comply with current Good Manufacturing Practice regulations. France leads US import supply for this heading, with Thailand and Spain also significant sources — a supplier mix that reflects both established European pharmaceutical manufacturing and growing Asian API production capacity.
AI-written summary of the official U.S. Census Bureau trade figures on this page — verify before relying on it.
Bulk aspirin imported as a drug substance must come from an FDA-registered foreign drug establishment. The importer or US agent must submit prior notice, and the shipment is subject to FDA examination at the port of entry. A Drug Master File (DMF) is typically required for pharmaceutical customers downstream. Admissibility and classification are complex; consult a licensed customs broker and regulatory counsel familiar with FDA drug import procedures.
The US schedule separates the pure ortho-acetylsalicylic acid (2918221000) from its salts and esters (2918225000). Salts such as calcium acetylsalicylate and esters used in prodrug formulations fall under the latter line. The distinction matters because duty rates and any applicable trade-remedy exposure may differ between the two lines, and the end-use application (e.g., pharmaceutical versus flavoring) can also influence classification.
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Monthly import values over time
HS10 import codes under this HS6 parent, each with its own page. Source: U.S. Harmonized Tariff Schedule.
| Code | Description | Import Value | Effective Tariff % | Dutiable Share | Duty Collected |
|---|---|---|---|---|---|
| 2918221000 | ORTHO-ACETYLSALICYLIC ACID (ASPIRIN) | $1.2M | 6.59% | 101.45% | $77K |
| 2918225000 | SALTS AND ESTERS OF O-ACETYLSALICYLIC ACID | $5K | 6.50% | 100.00% | $333 |
HS10 export codes under this HS6 parent, each with its own page. Source: U.S. Schedule B export classification.
| Code | Description | Export Value |
|---|---|---|
| 2918220000 | O-ACETYLSALICYLIC ACID (ASPIRIN), SALTS AND ESTERS | $15K |
NUCLEIC ACIDS & SALTS; OTHER HETEROCYCLIC CMP, NES
HS 293499
POLYPEPTIDE PROTEIN& GLYCOPROTEIN HORMONES &DERIV
HS 293719
CMPDS CONT AN UNFUSED PYRIDINE RING ETC NESOI
HS 293339
BENZENE
HS 290220
HETEROCYCLIC COMP W NITROGEN HETERO-ATM ONLY NESOI
HS 293399
HETEROCYCLIC COMP WITH UNFUSED PYRAZOLE RING NESOI
HS 293319
| State | Imports | Exports | Balance |
|---|---|---|---|
| New York | $449K | -- | -$449K |
| New Jersey | $402K | $6K | -$396K |
| Pennsylvania | $233K | -- | -$233K |
| Port | Imports | Exports | Balance |
|---|---|---|---|
| NEW YORK, NY | $652K | -- | -$652K |
| NEWARK, NJ | $467K | -- | -$467K |
| SAVANNAH, GA | $46K | -- | -$46K |