U.S. exports of Enzymes & Prepared Enzymes (NESOI) (HS 350790) totaled $112.3M in August 2026.
Importers of Enzymes & Prepared Enzymes (NESOI) paid $5.5M in duties in August 2026, an average duty rate of 9.90% — duty actually collected as a share of the imports that cleared customs, not the published tariff schedule. Enzymes & Prepared Enzymes (NESOI) imports of $57.2M in August 2026 ran 18% below the year-to-date monthly average of $70.0M.
Last updated: August 2026 dataEnzymes not elsewhere specified — ranging from industrial proteases and lipases to specialty biocatalysts — are a high-value input for food processing, pharmaceutical manufacturing, biofuel production, and textile treatment. The US schedule separates penicillin G amidase (3507902000), a pharmaceutical-grade enzyme used in antibiotic synthesis, from all other enzymes and prepared enzymes (3507907000), a distinction that signals different end-use regulatory pathways. Denmark and Japan lead US imports, consistent with the global dominance of Scandinavian and Japanese enzyme producers in industrial biotechnology. Enzyme preparations intended for food use are subject to FDA oversight, while pharmaceutical-grade enzymes may require additional agency review depending on their intended application.
AI-written summary of the official U.S. Census Bureau trade figures on this page — verify before relying on it.
1.1K import shipments a month
Penicillin G amidase (3507902000) is singled out because it is a pharmaceutical-grade enzyme with a specific and narrow application: catalyzing the hydrolysis of penicillin G to produce 6-aminopenicillanic acid (6-APA), the core building block for semi-synthetic antibiotics. Its separation from the general enzyme NESOI line (3507907000) allows customs authorities to track this strategically important pharmaceutical input distinctly from commodity industrial enzymes.
Food-grade enzymes must come from an FDA-registered foreign facility, and Prior Notice must be filed before arrival. The importer should confirm that the enzyme has GRAS status or an applicable food additive regulation for its specific food-use application. Technical documentation — including the enzyme's activity specification, source organism, and intended use — should be retained to support both FDA admissibility review and correct HTS classification.
Subheading 1 of 2 in heading 3507
Subheading 350790 · $112.3M of $112.7M
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ImportsExports
Imports
$57.2MYoY · free account
Exports
$112.3MYoY · free account
12-mo low · imports
Low · free accountOver the twelve months to August 2026, the U.S. imported $836.0M of Enzymes & Prepared Enzymes (NESOI) and exported $1.3B.
Through August 2026. Source: U.S. Census Bureau.
HS10 import codes under this HS6 parent, each with its own page. Source: U.S. Harmonized Tariff Schedule.
| Code | Description | Imports for consumption | Average duty rate | Dutiable Share | Duty Collected |
|---|---|---|---|---|---|
| 3507907010 | Proteases, Amylses, Lipases, Cellulases, Pectnases, Etc | $28.3M | 10.43% | 86.89% | $3.0M |
| 3507907080 | Enzymes and Prepared Enzymes, NESOI | $27.5M | 9.36% | 78.32% | $2.6M |
| 3507902000 | Penicillin G Amidase | — | -- | -- | -- |
| 3507907000 | Enzymes and Prepared Enzymes, NESOI | — | -- | -- | -- |
HS10 export codes under this HS6 parent, each with its own page. Source: U.S. Schedule B export classification.
| Code | Description | Export Value |
|---|---|---|
| 3507907000 | Enzymes and Prepared Enzymes, NESOI | $110.0M |
| 3507902000 | Penicillin G Amidase | $2.3M |
Import lines come from the U.S. Harmonized Tariff Schedule and export lines from Schedule B. The two are numbered by different agencies, so the same 10-digit code can appear in both tables describing a different product.
Exports · August 2026
destination
customs district
origin
entry
rate provision · imports
16.9% enters free of duty; duty collected equals 9.90% of imports for consumption.