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U.S. exports of enzymes & prepared enzymes (nesoi) (HS 350790) totaled $92.7M in July 2026.
Importers of Enzymes & Prepared Enzymes (NESOI) paid $4.9M in duties in July 2026 — an effective duty rate of 9.6% on $50.5M in dutiable value, based on actual customs collections rather than the published tariff schedule. Enzymes & Prepared Enzymes (NESOI) imports of $61.3M in July 2026 ran 15% below the year-to-date monthly average of $71.8M.
Last updated: July 2026 dataEnzymes not elsewhere specified — ranging from industrial proteases and lipases to specialty biocatalysts — are a high-value input for food processing, pharmaceutical manufacturing, biofuel production, and textile treatment. The US schedule separates penicillin G amidase (3507902000), a pharmaceutical-grade enzyme used in antibiotic synthesis, from all other enzymes and prepared enzymes (3507907000), a distinction that signals different end-use regulatory pathways. Denmark and Japan lead US imports, consistent with the global dominance of Scandinavian and Japanese enzyme producers in industrial biotechnology. Enzyme preparations intended for food use are subject to FDA oversight, while pharmaceutical-grade enzymes may require additional agency review depending on their intended application.
AI-written summary of the official U.S. Census Bureau trade figures on this page — verify before relying on it.
996 shipments/mo
Penicillin G amidase (3507902000) is singled out because it is a pharmaceutical-grade enzyme with a specific and narrow application: catalyzing the hydrolysis of penicillin G to produce 6-aminopenicillanic acid (6-APA), the core building block for semi-synthetic antibiotics. Its separation from the general enzyme NESOI line (3507907000) allows customs authorities to track this strategically important pharmaceutical input distinctly from commodity industrial enzymes.
Food-grade enzymes must come from an FDA-registered foreign facility, and Prior Notice must be filed before arrival. The importer should confirm that the enzyme has GRAS status or an applicable food additive regulation for its specific food-use application. Technical documentation — including the enzyme's activity specification, source organism, and intended use — should be retained to support both FDA admissibility review and correct HTS classification.
HSChapter 35
Subheading 1 of 2 in heading 3507
Subheading 350790 · $61.3M of $62.0M
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HS10 import codes under this HS6 parent, each with its own page. Source: U.S. Harmonized Tariff Schedule.
| Code | Description | Import Value | Effective Tariff % | Dutiable Share | Duty Collected |
|---|---|---|---|---|---|
| 3507907080 | Enzymes and Prepared Enzymes, NESOI | $36.2M | 7.52% | 88.79% | $2.7M |
| 3507907010 | Proteases,Amylses,Lipases,Cellulases,Pectnases,Etc | $25.1M | 8.48% | 73.06% | $2.1M |
| 3507902000 | Penicillin G Amidase | $0 | -- | -- | -- |
| 3507907000 | Enzymes and Prepared Enzymes, NESOI | $0 | -- | -- | -- |
HS10 export codes under this HS6 parent, each with its own page. Source: U.S. Schedule B export classification.
| Code | Description | Export Value |
|---|---|---|
| 3507907000 | Enzymes and Prepared Enzymes, NESOI | $89.9M |
| 3507902000 | Penicillin G Amidase | $2.9M |
Import lines come from the U.S. Harmonized Tariff Schedule and export lines from Schedule B. The two are numbered by different agencies, so the same 10-digit code can appear in both tables describing a different product.
ImportsExports
Imports
$61.3MYoY · Pro
Exports
$92.7MYoY · Pro
12-mo low · imports
YoY · ProThrough July 2026. Source: U.S. Census Bureau.
Exports · July 2026
destination
customs district
origin
entry
rate provision · imports
17.7% enters free of duty; the effective duty rate is 7.91%.