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HSChapter 29
U.S. imports of pyrimidine & piperazine ring compounds (other) (HS 293359) totaled $117.6M in April 2026, traded with 36 countries.
Importers of Pyrimidine & Piperazine Ring Compounds (Other) paid $1.7M in duties in April 2026 — an effective duty rate of 6.7% on $25.8M in dutiable value, based on actual customs collections rather than the published tariff schedule. Pyrimidine & Piperazine Ring Compounds (Other) imports of $117.6M in April 2026 ran 29% above the year-to-date monthly average of $91.0M.
Last updated: April 2026 dataPharmaceutical and agrochemical compounds containing pyrimidine or piperazine ring systems span a wide functional range under this heading, from antihistamines and antinauseants (2933592100) to antidepressants and tranquilizers (2933594600) and multiple pesticide subheadings (2933590500, 2933591000, 2933591500, 2933591800). The US tariff schedule subdivides these compounds extensively by aromatic character, end-use category, and whether they fall under Additional US Note 3 to Section VI — a classification distinction that directly affects duty treatment. Importers of pharmaceutical active ingredients in this heading should confirm FDA drug-substance registration status, while pesticide-use compounds require EPA registration review at entry. The breadth of the heading means misclassification risk is high; a single molecule may qualify under several candidate subheadings depending on its primary commercial use.
AI-written summary of the official U.S. Census Bureau trade figures on this page — verify before relying on it.
The US tariff schedule repeatedly bifurcates subheadings between aromatic/modified-aromatic compounds and all others. This chemical-structure distinction determines which 10-digit line applies and can affect the applicable duty rate, so importers should confirm the compound's aromatic character with a chemist or customs specialist before filing.
Yes. Bulk drug substances and finished dosage forms classified here are subject to FDA admissibility review. Importers must ensure the product is covered by an active Drug Master File or IND/NDA as appropriate, and shipments may be detained if the foreign manufacturer is not on FDA's approved establishment list. Consult a licensed customs broker or regulatory counsel for specific admissibility requirements.
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| Country | Imports | Exports | Balance |
|---|---|---|---|
| SWITZERLAND | $63.3M | $311K | -$62.9M |
| BRAZIL | -- | $12.0M | +$12.0M |
| CHINA | $11.1M | $287K | -$10.8M |
| IRELAND | $8.1M | -- | -$8.1M |
| INDIA | $7.6M | $108K | -$7.5M |
Monthly import values over time
HS10 import codes under this HS6 parent. Source: U.S. Harmonized Tariff Schedule.
| Code | Description | Import Value | Effective Tariff % | Duty Collected |
|---|---|---|---|---|
| 2933595300 | OTHER AROM OR MOD-AROM DRUGS CONT A PYRIMID ETC | $85.6M | 6.50% | $980K |
| 2933593600 | OTHER AROM OR MOD-AROM ANTI-INFECTIVE AGENTS | $9.7M | 6.50% | $29K |
| 2933591500 | OTHER PESTICIDES CONT A PYRIMIDINE RING ETC | $6.0M | 6.54% | $264K |
| 2933599500 | OTHER(EXCL AROM OR MOD-AROMO) CMPDS CONT A PYR ETC | $5.4M | 7.55% | $373K |
| 2933595900 | OTHER DRUGS (EXCL AROM OR MOD-AROM) CONT A PYR ETC | $4.7M | 3.70% | $2K |
| 2933597000 | PROD IN U.S. NOTE 3 TO SEC 6 CONT A PYRIMID RN ETC | $3.1M | 6.50% | $73K |
| 2933598000 | OTHER AROM OR MOD-AROM CMPDS CONT A PYRIM RNG ETC | $2.1M | 6.50% | $9K |
| 2933594600 | ANTIDEP., TRANQ., ETC. W/ PYRIMIDINE RING | $340K | 6.50% | $419 |
| 2933598500 | 2-AMINO-4-CHLORO-6-METHOXYPYRIMIDINE; ETC. | $310K | -- | -- |
| 2933592100 | ANTIHISTAMINES, INCLUDING ANTINAUSEANTS | $301K | -- | -- |
| 2933591800 | OTHER PESTICIDES (EXCL AROM OR MOD-AROM) CONT ETC | $21K | 6.50% | $1K |
| 2933591000 | AROMATIC OR MODIFIED AROMATIC HERBICIDES ETC | $0 | -- | -- |
| 2933592200 | NICARBAZIN AND TRIMETHOPRIM | $0 | -- | -- |
OTHER AROM OR MOD-AROM DRUGS CONT A PYRIMID ETC
OTHER AROM OR MOD-AROM ANTI-INFECTIVE AGENTS
OTHER PESTICIDES CONT A PYRIMIDINE RING ETC
OTHER(EXCL AROM OR MOD-AROMO) CMPDS CONT A PYR ETC
OTHER DRUGS (EXCL AROM OR MOD-AROM) CONT A PYR ETC
PROD IN U.S. NOTE 3 TO SEC 6 CONT A PYRIMID RN ETC
OTHER AROM OR MOD-AROM CMPDS CONT A PYRIM RNG ETC
ANTIDEP., TRANQ., ETC. W/ PYRIMIDINE RING
2-AMINO-4-CHLORO-6-METHOXYPYRIMIDINE; ETC.
ANTIHISTAMINES, INCLUDING ANTINAUSEANTS
OTHER PESTICIDES (EXCL AROM OR MOD-AROM) CONT ETC
AROMATIC OR MODIFIED AROMATIC HERBICIDES ETC
NICARBAZIN AND TRIMETHOPRIM
HS10 export codes under this HS6 parent. Source: U.S. Schedule B export classification.
| Code | Description | Export Value |
|---|---|---|
| 2933590500 | PESTICIDES CONT A PYRIMIDINE RING OR PIPERAZINE RN | $14.6M |
| 2933595960 | DRUGS CONT A PYRIMIDINE OR PIPERAZINE RING ETC | $11.8M |
| 2933599550 | CMPDS CONT A PYRIMIDINE OR PIPERAZINE RING, NESOI | $3.9M |
PESTICIDES CONT A PYRIMIDINE RING OR PIPERAZINE RN
140.4K kg
DRUGS CONT A PYRIMIDINE OR PIPERAZINE RING ETC
186.3K kg
CMPDS CONT A PYRIMIDINE OR PIPERAZINE RING, NESOI
45.5K kg
LACTAMS (EXCLUDING 6-HEXANELACTAM) NESOI
HS 293379
| State | Imports | Exports | Balance |
|---|---|---|---|
| Puerto Rico | $73.2M | -- | -$73.2M |
| Missouri | $8.6M | $15.0M | +$6.4M |
| Kentucky | $7.1M | $2.5M | -$4.6M |
| Port | Imports | Exports | Balance |
|---|---|---|---|
| SAN JUAN INTERNATIONAL AIRPORT, PR | $60.5M | -- | -$60.5M |
| CHICAGO, IL | $14.6M | $8.5M | -$6.1M |
| NEW YORK, NY | -- | $12.6M | +$12.6M |