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HSChapter 28
U.S. exports of actinium-225, actinium-227, californium-253 & related isotopes (HS 284442) totaled $7.6M in June 2026, traded with 32 countries.
Actinium-225, actinium-227, californium-253, and the other specific isotopes enumerated in this heading are high-value radioisotopes with emerging applications in targeted alpha therapy (TAT) for cancer treatment and in neutron source technology. All US imports enter under tariff line 2844420000. Because no top supplier countries are available for this heading, origin patterns cannot be characterized here, but the global supply of these isotopes is highly concentrated among a small number of national laboratory and reactor operators worldwide. NRC licensing and, for certain isotopes, Department of Energy authorization are prerequisites for any commercial import.
AI-written summary of the official U.S. Census Bureau trade figures on this page — verify before relying on it.
Actinium-225 is a key alpha-emitting isotope used in targeted alpha therapy, a cancer treatment modality that delivers highly localized radiation to tumor cells. Its short range in tissue minimizes collateral damage, making it attractive for oncology applications. Global supply is extremely limited because Ac-225 is produced in only a handful of nuclear reactors and accelerators worldwide, creating significant supply-chain concentration risk for pharmaceutical developers.
Heading 284442 enumerates specific isotopes by name, and only those explicitly listed—including californium-253—fall here. Other californium isotopes not enumerated in this heading would be classified under the residual radioactive elements heading (284443). Importers should verify the exact isotope identity on the commercial invoice and certificate of analysis to ensure correct classification, as misclassification between these headings can affect licensing documentation requirements.
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HS10 export codes under this HS6 parent, each with its own page. Source: U.S. Schedule B export classification.
| Code | Description | Export Value |
|---|---|---|
| 2844420000 | ACTINIUM-225, ACTINIUM-227, CALIFORNIUM-253, ETC | $7.6M |
URANIUM ENRICHED IN U235 ETC. PLUTONIUM ETC.
HS 284420
ANHYDROUS AMMONIA
HS 281410
NATURAL URANIUM & COMPOUNDS, ALLOYS & CERAMICS ETC
HS 284410
TUNGSTATES (WOLFRAMATES)
HS 284180
ALLOYS, DISPERSIONS,ISOTOPES & COMPOUNDS NES
HS 284443
ALUMINUM OXIDE, EXCEPT ARTIFICIAL CORUNDUM, NESOI
HS 281820
| State | Imports | Exports | Balance |
|---|---|---|---|
| Washington | -- | $2.8M | +$2.8M |
| Indiana | -- | $2.6M | +$2.6M |
| New Jersey | -- | $1.1M | +$1.1M |
| Port | Imports | Exports | Balance |
|---|---|---|---|
| SEATTLE-TACOMA INTERNATIONAL AIRPORT, WA | -- | $2.7M | +$2.7M |
| CHICAGO, IL | -- | $2.2M | +$2.2M |
| NEWARK, NJ | -- | $897K | +$897K |